My husband has just completed dose 2 of 6 of Pluvicto and no, he is not like the actors in the ads. From the first treatment, he suffered from extreme fatigue for up to a week post treatment, then a lack of appetite for the next week or two. Severe dry mouth is a constant. We have started the cycle over with treatment 2.

His PSA was over 200 at first treatment and rose to 360 the month following. We’ve been told to expect a rise for at least the first 2 treatments, but I fear we waited too long to begin them.