@kjane322
That is great that your MC is in remission from leaving off the Aleve. It is basically an OTC NSAID and NSAIDs can certainly cause MC and GI bleeds too! My husband has RA since he was 25 …. He had a close to death GI bleed from the treatment of RA so many years ago (1977) he was diagnosed with RA and the first treatment at that time was 16 aspirin a day! Then NSAIDS were created and probably he took those at least 10 years. 9 units of blood as quickly as they could transfuse into him. The surgeon wasn’t hasty to perform surgery and the bleeding stopped in about 3 days (the surgeon said to us “he is a healing son of a gun”)! NSAIDS were removed from his medications and he was referred to a rheumatologist. So many medications over the years to help with RA inflammation and pain….. (even opioids). 2 years ago he stopped the opioids cold turkey (he never had any withdrawal symptoms, not that he could tell and I didn’t know he had stopped them). All the newest meds (no more NSAIDS) he has had many….one of the first was gold salts injections, so many I can’t recall them all. He takes a biologic infusion now, Actamera. He has had other biologics too. Eventually each medication he takes they stop helping and his rheumatologist prescribes another.
To have MC and GIs are so lax to find something other than Budesonide to treat the symptoms for me to eat as Wayne Persky says has been the best way to treat MC for me.
My husband occasionally has to take prednisone for flare ups but he hates how it causes him to feel…… the effects of steroids aren’t a good thing for us but I take budesonide when I have to.
I am soooooo Thankful that budesonide is now available when a person is diagnosed with MC and the symptoms are 24/7….. mine were and I am grateful my GI had my biopsies tested for MC…..no way could I havre continued to thrive with the 24/7 diarrhea that controlled every moment for 7 months of my life…….. the budesonide as you said got the MC under control after 4 months from start to weaning.
Now to keep flare ups at bay or away is my goal!!!!
Vomiting had become an issue and that caused me to adhere to the foods that Wayne Persky says are the only way to heal the inflammation. I am not a big eater (always a bit of a picky eater)…… I know I certainly cannot loose any more weight and likely won’t gain much unless I have to depend on a steroid to keep me from flaring up. I don’t know if that is a side effect of budesonide but I know weight gain is a side effect of many steroids.
I am so glad the budesonide works so well for you plus the elimination of Aleve. A known issue for MC are medications…… PPIs are another but GIs prescribe them as though they don’t know they are an issue for patients with MC……
*A portion of a newsletter from the MC foundation:

Take 3 capsules each morning and see me in 6 months.
As part of their treatment recommendations, most gastroenterologists advise MC patients to avoid certain drugs that are known to be commonly associated with the onset of microscopic colitis.
One of the first classes of medications recognized to cause microscopic colitis is known as nonsteroidal anti-inflammatory drugs (NSAIDs). Since then, additional drugs have been added to the list, including antibiotics, proton pump inhibitors (PPls), selective serotonin reuptake inhibitors (SSR|s), serotonin-norepinephrine reuptake inhibitors
(SNRIs), tricyclic antidepressants, angiotensin-converting enzyme (ACE) inhibitors, beta blockers, statins, and bisphosphonates, There are surely others that have not yet been identified

*My GI prescribed me omeprazole for the reflux that became vomiting……..
Sad that they treat patients with drugs known to cause MC…….