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Don’t know what I don’t know…diagnosed 5/13/25
Prostate Cancer | Last Active: 5 days ago | Replies (18)Comment receiving replies
Thank you for taking the time for such a detailed reply. I'll try to hit all your points.
> Last PSA prior to 2025 was in 2015 and that was 0.4. My PCP retired and I didn't pay much attention to it (my bad) since my family history is heart disease with zero cancer. All males in my family for the last 5 generations have died of heart disease prior to their 69th birthday, except for me. I really thought I'd be dead by now.
> PNI (perineural invasion) was noted on the biopsy report. No MRI. Pathologic stages are entered as percentage scores in a Partin Table:
Organ confined - 19% Capsular penetration - 30%
Seminal vesicle - 28% Lymph node - 22%
> There is a very brief mention of cribriform / intraductal histology related to a recommendation for Germline Genetic Testing.
> Radiation treatment was briefly discussed but options will be detailed once PET results are received.
> I started Orgovyx the day after the PET
I think I got it all. Thanks again!
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Ten years between PSA tests is a long time - as former Pres Biden just found out. But, what’s done is done……
These things are rarely straightforward; the more you get into this, it sometimes gets more complex. You’ll need to dig into it, learn more, self-advocate, and share in the decision-making to get the best outcomes.
Regarding exercise —> walking 3-4 miles/day is great (and well-documented) for overall health. But, the toxic side-effects of ADT require a bit more (as this clinical trial demonstrated): https://journals.lww.com/acsm-msse/fulltext/2023/04000/resistance_exercise_training_increases_muscle_mass.2.aspx)
However, walking 3-4 miles/day will help with the emotional/mental health side-effects of ADT (as these doctors recommended in this PCRI conference a few years ago): https://m.youtube.com/watch?v=8n0cIhamFvo
But, since you might not be able to exercise the way that these doctors recommended: https://m.youtube.com/watch?v=YE61HSAsFb0), you’ll have to come up with alternatives to offset the physical side-effects of ADT —> alternative exercises like like using your own bodyweight, or trying TRX, or taking a water exercise class (which is what I did at one point). There are many resistance-training alternatives to weightlifting.
Another question —> You’ve mentioned “PET/CT” and “PET results.” Is that a PSMA PET scan that you recently had?
All the things you mentioned will guide discussions with your medical team. If they use standard NCCN guidelines (see attached), there are general treatments they’ll recommend for you. But, you’ll have the final say in what happens.