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Diagnosed with Ameloblastoma

Head & Neck Cancer | Last Active: 3 hours ago | Replies (260)

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@tomschwerdt

My ameloblastoma is mandibular instead of maxillary, but conservative surgery bought me 15+ years of full functionality with my original jawbone.

Ameloblastomas usually grow very slowly - and 15+ years later when it came back I have (and chose) the option of genetically targeted chemotherapy: 5 pills a day. Chemo is very slowly shrinking my ameloblastoma. I'm much more comfortable with the chemo side effects than radical surgery.

Everyone has to make their own choice.

Important note: Mandibular ameloblastomas (including mine) mostly have the BRAF V600E mutation. Maxillary ameloblastomas generally have different mutations. When I did my deep dive into the literature, I focused on mandibular because that's what I have. LMK if you want help looking into the mutations behind maxillary ameloblastomas.

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Replies to "My ameloblastoma is mandibular instead of maxillary, but conservative surgery bought me 15+ years of full..."

Oh yes, any direction you can point me in in terms of the maxillary mutations would be most helpful.