@mnpat This is an interesting question. I am also looking forward to hearing responses from others. In the meantime here are some articles from a reliable website, the National Institute of Health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959222/ and https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206478/ They do point to the fact that this can be a problem. This would be a good discussion with your doctor and perhaps anesthesiologist prior to surgery.