The reason for the high dosage was I was on what is called the Ponticelli protocol for kidney failure. The protocol calls for alternating Predisone with a chemo drug for six months. On the first three days of the three months on Prednisone, I received three thousand mg injection each day. I got a kick out of the reaction of my Dr. when I mentioned this. He said, “Yes, 27 grams is a lot.” I guess it all depends on how it is expressed.