Mayo didn’t actually test those markers. I had asked my pcp to do my particle numbers, and then I joint Function Health, which is a lot of tests that get more into newer research, functional medicine (finding reason why)…
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ApoB is a protein, Lp(a) is a lipoprotein:
ApoB is a protein that carries fats, while Lp(a) is a specific lipoprotein particle containing apoB and apo(a). o
Lp(a) is a subset of ApoB-containing particles:
Lp(a) is one type of apoB-containing particle, but it is not the only one. o
Lp(a) is an independent risk factor:
Lp(a) levels are a separate predictor of cardiovascular risk, independent of total LDL cholesterol or apoB levels. • Genetic Influence:
Lp(a) levels are largely determined by genetics, while ApoB levels are influenced by lifestyle and other factors.
Importance of both measures:
Measuring both ApoB and Lp(a) can provide a more comprehensive assessment of cardiovascular risk than measuring LDL
cholesterol alone. "
In summary: ApoB is a marker for the number of atherogenic lipoproteins, while Lp(a) is a specific lipoprotein particle that is a distinct risk factor for heart disease. Both measures are important for assessing cardiovascular risk.