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← Return to Trouble going below 3mg
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Polymyalgia Rheumatica (PMR) | Last Active: Jun 10 3:21pm | Replies (27)
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Does everybody taking a biologic or DMARD get to 0mg prednisone?
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No ... only about half of the patients on Actemra were able to get to 0 mg of prednisone. I was part of the lucky half ... I guess.
In the Giacta trial for GCA approximately 3 times more patients were able to achieve a "sustained remission" in 52 weeks compared to Prednisone alone. The cumulative dose of Prednisone needed for remission was much less and also statistically significant.
https://www.nejm.org/doi/full/10.1056/NEJMoa1613849
Replies to "Does everybody taking a biologic or DMARD get to 0mg prednisone? -------------------- No ... only about..."
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"No ... only about half of the patients on Actemra were able to get to 0 mg of prednisone. I was part of the lucky half ... I guess."
With all you've been through, you deserved that bit of luck.
Does that mean the unlucky patients were/are taking both prednisone and actemra? If you cannot get to 0mg prednisone you stop taking actemra? Must be interleukin 6 related?
I still do not personally know anyone who like me has pmr, in 7 years.