I was on .175 daily for years - and my thyroid went crazy high. Had to decrease my dosage to .150, which really slows me down but with the higher dose they were afraid of my heart (I’m 75). I have had an unstable thyroid since I was28, and basically have felt normal for 4 days in my life (when my thyroid was decreasing and hit normal levels)it was Labor Day 1978 - I’m an anomaly so depending what your situation is just watch it and control it. When they found my issue my tsh was so high they had to put me on blood pressure medicine immediately. I am losing some weight now little by little but I also have to say my pain and aches have drastically diminished with being off now for two months. Not sure if any of this helps but my only advice would to be watch side effects while on envenity. Hope it works for you. Keep us posted.