I’m not a doctor, let me start there, but it sounds to me with weight gain that you could possibly have Hashimoto’s. I suffer from it and also Hypothyroidism for which I take Synthroid 75 mcg. I would ask your doctor to run a Thyroid Panel and include testing of TSH, T3-free, T4-free and TPO Antibodies (which is where Hashimoto’s shows up). My husband and I were doing the Weight Watchers Diet and I was gaining a pound a day and he was loosing! That’s how I knew something was drastically wrong. I am feeling so much better and I also have eliminated eating gluten, dairy and soy which are big no no’s with Hashimoto’s. I wish you well and good luck!