Thank you for responding. Did you have extreme joint swelling around your affected joints at any point? The swelling in my knees, legs and one ankle was so drastic a few days after the infusion, I couldn't bend them at all. I was traveling away from home and had to return to see my doctor. It was frightening. Exercise does help now but getting up in the morning after lying down all night is very painful. I will report to the FDA. Again, thank you!