Good morning! Im taking 2000 mg a day 2 morning 2 night I was also on this last year on firsr round of this experience this time i think im better prepared last time (I was on it for 6 months) it took about 4 weeks for side effects to start like hand foot being tired This time im prepping my skin im already using socks at night to heavily coat my feet with good ole fashion bag balm along with Eucrin 40 percent lotion also on my hands with a pair of chepo gloves Drinking lots of water and just ordered last week and additive called Nectar that is sugar free and lots of all natural ingredients including helyam sodium which is more natural My onco also advised me to make sure to eat a full meal before taking take meds within 30 minutes of eating along with ZOFRAN for the nausea. this time im following exactly what she said! Also to lay down for about 30 to 45 minutes after taking So im into day 5 on this round and had no effects (even though last time took a while) because im trying everything possible to stay ahead! Is this your first time on it? I lost the first time way too much weight over 30 lbs but it was after the dose of Oxaliplatinthat did me in ! I had to get hydrated iv for almost 2 weeks! They stopped it increased the Capaecitabian to 3000 mg per day that was rough had mouth sores but she got me Magic Mouth wash I also took Benadryl and it stopped it! so this time i have a bottle here as a safeguard! ok im off to get my port flushed ugh! yes lets keep in touch and compare notes and support each other! xo