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@jeffmarc

I forgot to mention. During those eight years I was on ADT, if I reduced the drug I was using at all either ADT or Zytiga, Even a little bit, My PSA would go up very quickly. I’m pretty sure that is due to the BRCA2 since I am a Gleason 4+3.

2 years ago I tried going from 4 Zytiga to 3 Zytiga and my PSA rose from .2 to 1 in 18 days.

Get tested within 1 month of stopping ADT.

Discuss going on the PARP Inhibitor early with your doctor. There’s been a lot of buzz lately about it making a big difference long term. There’s even been a study using it early with Enzalutamide. I don’t know if it would be beneficial for you now, but The doctor you have probably has some good information about it.

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Replies to "I forgot to mention. During those eight years I was on ADT, if I reduced the..."

Thanks for the information Jeff, I will discuss the treatment options you mentioned with my oncologist.
Tom