If you trust your doctor fully and have faith in his advice and you have done your own research go with him; if you're not sure he has the answer seek a second opinion. My kidney cancer was diagnosed a little over two years ago and urologist advised total nephrectomy of kidney with malignant lesion. Because of my age, 81 at time of diagnosis, I ruled out surgery and have been on Keytruda for a little over a year and also had high dose radiation to stop bleeding from lesion about a year ago. Because of severe skin rash from immunotherapy, after 14 treatments I will probably stop treatment, which was a palliative in any case. These decisions are hard to make, but after a decision is made it is best not to dwell on your cancer but enjoy each day given to you.