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Perineurial invasion. 1 out of 10 samples cancerous. Treatment?

Prostate Cancer | Last Active: 3 hours ago | Replies (19)
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@sarahsmithsarahsmith

His Psa was 5.6.
He gets that test yearly due to blood in his urine for the last 20 yrs where they can’t find a chase, so has been closely monitored for years.

I don’t know what his mri indicated.

His results showed 9 samples that were not cancer, and one that said “A minute focus of adenocarcinoma with Perineurial Nerve invasion”. No Gleason score given.

I’ll ask when I go with him to his appointment on Friday June 6th.

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Replies to "His Psa was 5.6. He gets that test yearly due to blood in his urine for..."
heavyphil | @heavyphil | 2 days ago

Yes, the MRI is very important. Also find out if he had a transrectal or transperineal biopsy.
A Trans - Perineal affords greater access to the entire gland and can get to areas the transrectal cannot reach without causing injury.
As @jeffmarc points out, there might not even be enough cancer to warrant Gleason scoring, but the words ‘adenocarcinoma’ and ‘perineural invasion’ usually are mentioned in a Gleason score framework.
At the very least get a second pathologist to look at the slides - very easy to have images/slides sent to a patho at a leading cancer center. Best,
Phil

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