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Tagging @taterjoy who has talked about lamotrogine (anti-seizure) med for migraine to share about use of this medication and how it's gone.

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Useless. None of the meds for migraine I have tried worked and I have tried at least 50

I tired several anti seizure meds to prevent migraine and none helped. Depokote and Lamotrigine did not help, and made me a bit sleepy. The only category that has helped prevent my headaches is CGRP, which are once per month self-injections. I still have migraines but much less often and usually not nearly as severe. The indomethacin and caffeine I take nightly to prevent a different type of headache, a nocturnal occurring severe inflammatory type headache unresponsive to anything else. I hope the Lamotrigine will help her!