My husband had similar symptoms in both legs. After several labs showing nothing, he got back on Doxycycline for couple of days, and all symptoms went away. We both have Lyme disease and only take Doxy when we have flare ups. The ticks that infected us were like grains of sand. We live in the city, but the ticks attached while walking in a small park. About the only lab we found that specializes in Lyme is IGENEX in California. Lyme "the Great Imitator" can mimic almost any disease. It's everywhere inspite of what we're told. You don't have to be in the forest to be bitten by ticks. We've dealt with this for 5 years and you'd think we would have suspected his leg issues to be Lyme related, instead of going thru 2 specialists, tons of labs, prescriptions and then one morning as his legs were worsening I looked at him "Duh? ... maybe Lyme flare up?" Two days later .. all symptoms gone! The Spirochettes (Lyme bacteria) love 'traumatized' areas to attack and settle in. We found a Lyme-literate/trained doctor by visiting website ILADS early into our journey because few doctors have been trained to diagnose/treat Lyme and the CDC's guidelines for labs/testing is very antiquated and inefficient (Surprise, Surprise!:) After about 3 months of taking/rotating several different antibiotics, antivirals, antifungals, etc., we got the symptoms under control and for past 4 years have been almost totally on herbal supplements to keep our autoimmune system at it's best. We're told Lyme is never cured; it forms a shell-like covering and goes into kind of a dormancy until 'trauma' or weak immune system presents, then it becomes active. As with cancer patients, our doctor told us very early on to cut out sugar and gluten, which has helped deplete inflammation. Hope this rambling helps.