That’s a very good question, @susanjohnston!

When I began taking Reclast c. 2011, I thought it was the wonder drug that would keep my OP at bay. However, a few years after what I thought would be my last infusion, I had an undiagnosed compression frax but my DEXA numbers weren’t really much different.

In 2022, I discussed the earlier pain in my back with my rheumatologist who suggested that I might have had a vertebral frax and ordered an x-ray; by that time, I had three of those little buggers. The doc then suggested I try a new treatment - Tymlos. My trials with Tymlos are well documented in other posts on this forum.

After discontinuing Tymlos, because of the many issues, I did a complete year of Evenity, which was uneventful in the adverse reaction category. Immediately following the last injection(s) of Evenity, I had a Reclast infusion and will likely have another in a few months.

In January 2026, I’ll have a DEXA which will tell me if Reclast is holding my gains steady or if another med will be necessary to build bone and remain steady with the gains.

That’s the long answer. The short answer is depending on the results of lab work and DEXA’s, the Reclast might or might not hold the gains we get from Tymlos and Evenity. It’ll be interesting to see what my doc prescribes for me next in the event something is necessary to keep me upright.

As a note, generally there is a “drug holiday” period after a few doses of Reclast, perhaps until a backslide is discovered through testing. From what I was able to learn, the biggest risk with Reclast is the likelihood of spontaneous femoral frax from too many infusions. I decided to take that risk.

Wishing you and everyone a sunny day! Cheers!