@mlor
What types of specialists are you and your son working with? Does he have a psychologist and psychiatrist? Has he had inpatient treatment?

It would be good to look at medication interactions to see if something we’d to change rather than throwing on a 4th medication to manage the panic attack side effects. I took Zoloft for panic attacks so it sounds like your son’s medication combination may be an issue.
1. https://www.drugs.com/sfx/invega-sustenna-side-effects.html
2. https://www.healthline.com/health/drugs/invega-sustenna-side-effects
3. https://www.medicine.com/drug/invega-sustenna
4. https://www.drugs.com/drug-interactions/seroquel-with-zoloft-1979-1274-2057-1348.html
5. https://statcarewalkin.com/info/can-you-take-zoloft-and-seroquel-together.html
6. https://www.medicine.com/interaction-checker/result
7. https://www.ehealthme.com/drug-interaction/zoloft/seroquel/