So far, I can see no real difference with the new enzymes. I think the diarrhea is due to having a gastric bypass in 2018, but I don’t remember the diarrhea starting until later, after I had been on antibiotics for something else. They thought I had SIBO (small intestinal bacterial overgrowth) and treated that with a specific antibiotic (xifaxin?) which worked but cost $2000 for two weeks. I was able to get samples to cover it that time. Now I am on Medicare which actually said they would pay for but at that point they were trying me on a different antibiotic (which did not work). I have an upcoming phone call with digestive disease nurse practitioner but I doubt she will try anything new before I have a colonoscopy in three weeks. I had been using a lot of immodium daily and she also prescribed Lomotil which helps. Thank you for your question and concern. Are you still taking Wegovy?