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COPD Bronchiectasis ABPA New: MAC & AFB

MAC & Bronchiectasis | Last Active: Oct 26, 2025 | Replies (10)

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Sorry to hear about your diagnosis. I can’t speak on the COPD or APBA but I think for many the MAC diagnosis is tough because it’s a chronic illness which requires daily intervention (airway clearance) plus if determined to be best, long term medication. I opted for the big 3 which is an antibiotic cocktail of arithromycin, rifabutin and ethambutol, the side effects of which can be tough. Labs to monitor, along with vision and hearing screening is required. Once the MAC infection is cleared the drugs are still taken for 12 months from that date. This forum does have a list of questions you can use to bring to your dr along with a wealth of information and support.

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Replies to "Sorry to hear about your diagnosis. I can’t speak on the COPD or APBA but I..."

@rmoore901 - Glad I saw this.
I have been on the big 3, three times a week, for 6 weeks. My daily cough disappeared within 10 days. I wasn't told to do airway clearance; was only told about the liver test (after 5 weeks mine was normal; I'll have another one in a couple months) and not about hearing and vision screening, although I was told that ethambutol (I think) can cause red-green colorblindness, which I haven't (yet) experienced. Doc said I may be able to go off the ethambutol in December (so far, the only bad side effect for me has been fatigue).

@rmoore901
I only took the Big 3 for 9 months and then stopped.