@japlok Kudos to you for doing all the work to ensure the best outcome for your spouse. My husband was diagnosed with AD in December 2024 and is currently taking Leqembi. The infusions are twice per month for 18 months. I would definitely get your loved one tested at Mayo Clinic to see if she qualifies for treatment. If you decide to begin the infusions of the approved drugs, hopefully you can do this close to your home in Indiana. Best of luck and keep us posted. I have found it can be helpful to read the posts of others on similar paths.