I spent about 45 years with migraines (no auras) on the left side of my head. Probably from a injury from horse riding accident at age 11. All I had for many years was aspirin until Acetaminophen and Ibuprofen were invented (yes, I'm that old.). Those OTC meds were not at all successful at getting rid of migraines. The best Rx drug I ever used for migraines was Caffergot (ergotamine with caffeine) but for some odd reason it was taken off the market about 10 or 15 years ago. It had worked like magic for me. Finally my doctor sent me to a pain specialist that specialized in a procedure to deaden the nerves in my neck. That Radiofrequency Nerve Ablation procedure was a true miracle! I've never had another migraine since and any headaches I do get are minor and go away on their own. A friend of mine with the same migraine problem had it performed by a different doctor with a poor outcome. Her headaches got worse. Just good luck for me or what? It took several visits to qualify for the procedure but was well worth the time and effort.