Estradiol in suppository form has helped me stop 3 consecutive UTI's. And also taking a probiotic. The decline in estrogen post menopause makes you more susceptible to UTI's ac to both my urologist and gynecologist. And for some reason the Probiotic is protective...maybe bc it also helps prevent the E Coli from establishing a stronghold in your gut???

I no longer need D-Mannose every day but do use short term it when I feel like my urine is starting to get cloudy again. If you are diabetic, you should talk to your endocrinologist b4 starting d-Mannose because it's a sugar. And avoid acidic food and drinks when taking -Mannose. Pub Med is helpful to look at clinical research results when evaluating supplement alternatives to antibiotics.

I’m so happy you found d mannose, it’s a lifesaver for me. I am 80 years old. After two years of bi monthly UTIs, I had a nurse turn me onto it at a CVS clinic. Then I also heard about methenamine, a sort of antibiotic or bacteria cleansing drug that works to remove bacteria from your bladder. Somehow, it’s not as likely to get you relying on it as if you are using the typical antibiotic for this disease. I was on a long trip and returned after a month in Europe with a UTI after having begun this routine, but I had no symptoms. Usually mine are a very strange severe aching inside, my very lower abdomen and pelvic area because I have a spastic bladder. Consequently with no symptoms except for tiredness turning into confusion and a leather G a friend grab me and took me to the ER where I stayed for two weeks on IV antibiotics. Sepsis! Yeah, it’s about 35% mortality rate so you don’t want to this. I suggest always having a bottle of antibiotics with you that work for you when you travel out of country, although you can point to different areas on your body and without speaking, the language easily get prescriptions unless you are quite far from a town,. I take one d-mannose both morning and night. It is not the usual sugar so really should not bother a diabetic in my opinion, but double check anyway. It taste sweet, but does not act like a sugar in your bladder, it simply coatsthe wall of the bladder so the bacteria have a barrier to fight through to get to a nesting spot. I have used estradial but prefer the vaginal suppository twice weekly. Using both it’s an option for severe cases. Good luck, this is a tough one for women —and for men surprisingly, as we age.