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@dadcue

" I haven't had any pain from the GCA or PMR since starting treatment. So it seems like my inflammation is mostly caused by IL-6."
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It seems to me that my IL-6 levels were causing all my problems since Actemra works well for me. It is strange that my IL-6 level has never been checked.

With all the emphasis of having a diagnosis to treat --- you would think they would want to know which cytokine to target and treat.

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Replies to "" I haven't had any pain from the GCA or PMR since starting treatment. So it..."

I assume they didn't test cytokines because there weren't many good alternatives to Actemra and Kevzara. I would think people who have the other kinds of cytokines more dominant would still get some relief from the biologic drugs, and could take less prednisone. The new drugs like Rinvoq for GCA might be a good alternative for people who don't respond well to Actemra. I've read there are several other new drugs in trials, so hopefully some of those would also be good alternatives.