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Recurrence in pelvic lymph node

Prostate Cancer | Last Active: 5 days ago | Replies (17)
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@treesqueak

Thanks for responding. After a biochemical recurrence one year after the prostatectomy, I received a six month Lupron shot (first time) and 36 rounds of radiation to the prostate bed (no lymph node radiation). Undetectable PSA for the next two years, until PSA
began to rise from .1 last September to 1.2 in March 2025. Received another Lupron shot on May 11, after PSMA showed uptake in a pelvic lymph node. Also, I'm concerned about a false positive since at the time I was recovering from a UTI. I will check out the PCIR meeting with Dr. Sholz.

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Replies to "Thanks for responding. After a biochemical recurrence one year after the prostatectomy, I received a six..."
jeff Marchi | @jeffmarc | May 26 10:56am

I went 3 1/2 years after my prostatectomy before my PSA started rising. I had Salvage radiation like you and my PSA started rising 2 1/2 years later. At that point, I was put on Lupron, And since I had 2 reoccurrence, there was no end date. After 2 1/2 years My PSA started rising again, and I went on abiraterone which kept me under control for 2 1/2 more years. Switched to Darolutamide And for 18 months, I’ve been undetectable after 15 years of PC. What i’m getting at is that you are in a situation where the correct drugs can keep you going for decades.

Yes, a UTI can raise your PSA. Get tested again find out what’s going on, Do not wait three months for a test get one done within a month or two at the most. Because you are on Lupron your PSA should drop to undetectable again. Actually, you should probably be on monthly PSA tests, I was put on monthly tests after my second reoccurrence.as have most of the people I know.

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