My experience, albeit not sure what the question is...

I did 12 months of Orgovyx, April 2023-April 2024. We measured PSA every three months since and T twice, at three - 328 and six months - 445, start point at treatment was 608. I have my upcoming Medicare annual wellness exam where my PCP does labs and he's included T

So at seven weeks, 45 may not be at the same rate mine was.

I am not sure why I recover so "well" after ADT. One theory I've seen literature on is the role of exercise in T recovery, I go to the gym most days, other days I ride my bike. I take care of all the yard work, active vacations where we hike a lot...so, maybe?

Perhaps the other question is TRT. The old adage is T is fuel for the fire...I am not sure of that. When I came off triplet therapy in May of 2017 with my last 90-day Lupron shot, my T recovered in a similar pattern. It was four plus years before my PCa started acting up. After 12 months of Orgovyx, my PCa lays quiet.

So, if T is the fuel, my PCa should have reared its ugly head long before it did after triplet therapy and even now, it should have. My medical team has no explanation, nor I have I found any in my literature searches. They and I just say, be happy, I am. There is a noticeable difference though as I say, the only noticeable difference between what I do on, and off ADT is how I feel doing it.

So, if your medical team does not want to discuss TRT, find others. I have fired two urologists and an oncologist over these 11+ years for their inability to actively listen, be open to other ideas and share in decision making.

Kevin