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Nanoknife for pancreatic cancer

Posted by hopefulandpositive @hopefulandpositive, Apr 10, 2024

Hi,
My husband was diagnosed with pancreatic adenocarcinoma 7 months ago. It is inoperable because it is wrapped tightly around superior mesenteric artery. He has done 12 cycles of chemo (oxaliplatin, irinotecan and floururacil) but tumor has not shrunk but it hasn't spread/grew either. We were told that continuing chemo after this many sessions is not good for his bone marrow and another chemo regimen is unlikely to going to help if 5FU didn't. We are given an option to go through Nanoknife procedure to "freeze" the tumor. The surgeon said he has done 200 procedures in the last 7 years and there are still some patients who haven't had any additional growth. Does anyone have experience with nanoknife? How was it? Any concerns? Just trying to get more information on this procedure as we were told to make a decision as soon as possible as the tumor hasn't spread to other organs yet and he will no longer be a candidate if it presents spread.

Interested in more discussions like this? Go to the Pancreatic Cancer Support Group.

namawg | @namawg | May 12 1:35pm
In reply to @hopefulandpositive "I highly recommend scheduling a visit with Dr. Chan at Iowa university to further discuss if..." + (show)
@hopefulandpositive

I highly recommend scheduling a visit with Dr. Chan at Iowa university to further discuss if you can. Of all the doctors who perform nanoknife that we met with (in addition to Dr. Chan, we met one in Illinois and another in Florida), he was the only one who approached it thoughtfully vs. pushing to perform a surgery and collect $$$s.
https://surgery.medicine.uiowa.edu/profile/carlos-chan

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My husband is in same situation. What doctor/ location in Florida? Not sure he is a candidate because he has history of low platelets

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Moderator
Colleen Young, Connect Director | @colleenyoung | May 24 12:16pm
In reply to @lulu789 "I would like to know more about Nanoknife" + (show)
@lulu789

I would like to know more about Nanoknife

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Hi @lulu789, I hope you saw the responses from fellow members about the nanaknife for pancreatic cancer here https://connect.mayoclinic.org/comment/1311078/ and here https://connect.mayoclinic.org/comment/1301694/

Yes, nanoknife is available at Mayo Clinic, Rochester. In fact, Dr. Rory Smoot, was the Mayo Clinic principal investigator in Rochester along with Dr. John Stauffer at Mayo in Jacksonville conducted this clinical trial:
- A Study to Evaluate the NanoKnife SYstem for Stage 3 Pancreatic Cancer https://www.mayo.edu/research/clinical-trials/cls-20509963

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1 reply
Moderator
Colleen Young, Connect Director | @colleenyoung | May 24 12:19pm
In reply to @colleenyoung "Hi @lulu789, I hope you saw the responses from fellow members about the nanaknife for pancreatic..." + (show)
@colleenyoung

Hi @lulu789, I hope you saw the responses from fellow members about the nanaknife for pancreatic cancer here https://connect.mayoclinic.org/comment/1311078/ and here https://connect.mayoclinic.org/comment/1301694/

Yes, nanoknife is available at Mayo Clinic, Rochester. In fact, Dr. Rory Smoot, was the Mayo Clinic principal investigator in Rochester along with Dr. John Stauffer at Mayo in Jacksonville conducted this clinical trial:
- A Study to Evaluate the NanoKnife SYstem for Stage 3 Pancreatic Cancer https://www.mayo.edu/research/clinical-trials/cls-20509963

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@lulu789, if you or anyone else has questions about nanoknife and the treatment of pancreatic cancer, you can ask Dr. Stauffer, Mayo Clinic. He will be answering people's questions next week on May 29 in this discussion:
- Pancreatic Cancer Q&A with Dr. Stauffer, Mayo Surgeon: May 29 https://connect.mayoclinic.org/discussion/pancreatic-cancer-qa-with-dr-stauffer-mayo-surgeon-may-29/

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1 reply
lulu789 | @lulu789 | May 25 10:07am
In reply to @colleenyoung "@lulu789, if you or anyone else has questions about nanoknife and the treatment of pancreatic cancer,..." + (show)
@colleenyoung

@lulu789, if you or anyone else has questions about nanoknife and the treatment of pancreatic cancer, you can ask Dr. Stauffer, Mayo Clinic. He will be answering people's questions next week on May 29 in this discussion:
- Pancreatic Cancer Q&A with Dr. Stauffer, Mayo Surgeon: May 29 https://connect.mayoclinic.org/discussion/pancreatic-cancer-qa-with-dr-stauffer-mayo-surgeon-may-29/

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Thank you so much for this information... I am so excited and hopeful to learn about this procedure. I am waiting for my information to be reviewed and waiting for the call to go to Mayo for an eval. ASAP... THank you for this ..

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