The only clinical trials I could find were done by the company that makes it and they were very low quality. That doesn't mean it doesn't work it just means there is no real evidence that it does. There is better evidence for K-2, which is much more affordable. This is not definitive but worth checking out and asking your doctor. https://www.frontiersin.org/journals/public-health/articles/10.3389/fpubh.2022.979649/full