I think it mostly depends on the duration of time you have been on Prednisone. I was on Prednisone for 12 years to treat PMR. I lost hope of ever tapering off Prednisone. I got conflicting advice about taking prednisone for the rest of my life. I mentioned this to my rheumatologigist who said I was "too young" to take prednisone for the rest of my life and 12 years was already too long.

The endocrinologist I saw said nobody should take Prednisone for years like I did. However, if I needed Prednisone to treat my autoimmune conditions there was nothing she could do.

I still needed 15 mg of Prednisone the first time I saw the endocrinologist. She referred me back to the rheumatologist to see what could be done. It was approximately a year later that Actemra was tried.

I hope Actemra works for you. I haven't been able to stop Actemra yet but I feel like I will be able to stop Actemra eventually. At least I'm off Prednisone. Actemra is easier to stop as long as PMR stays in remission. Actemra doesn't suppress my adrenal function.