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Taking Orgovyx long term

Prostate Cancer | Last Active: 2 days ago | Replies (47)

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@jime51

Isn't that the same outcome with ADT: it causes the cancer to "duck" but doesn't kill it, all the while the cancer cells are working to make their own testosterone?

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Replies to "Isn't that the same outcome with ADT: it causes the cancer to "duck" but doesn't kill..."

The cancer cells may or may not evolve to become castrate resistant, depending on how fully they're repressed. The trouble is that there is no medical way to detect if there are still some dormant cancer cells or micrometastases, waiting to start growing again some day.

ADT buys you time, and ARSIs like Apalutamide extend that time significantly for many prostate cancer patients. Radiation therapy also buys time (as does chemo, in the cast of polymetastatic PCa). They add up.