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How Concerning is this?

Prostate Cancer | Last Active: 4 days ago | Replies (27)

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@azp52

I dug into this some and found this
Why T Levels Might Appear Normal:
In some cases, even with Lupron's effectiveness in lowering testosterone, the initial T levels might still be within the normal range. This is because some testosterone comes from sources other than the testicles, and Lupron primarily targets testicular testosterone production.
Lupron, a gonadotropin-releasing hormone (GnRH) agonist, suppresses testosterone production, leading to a decrease in PSA levels, even if T levels remain within the normal range. This occurs because PSA, a marker for prostate cancer, is influenced by testosterone. While T levels might remain in the normal range, Lupron effectively reduces the stimulation of prostate cells that produce PSA, resulting in a lower PSA count.

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Replies to "I dug into this some and found this Why T Levels Might Appear Normal: In some..."

Yes, in very small amounts in the adrenal glands. It’s reported that the testicles produce around 95% of testosterone, while the adrenal glands account for the remaining 5%. That should help with your estimates.