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Interesting. You say that you’re on ADT, your PSA is lower m, but your T is not.
How ADT works —> ADT lowers T which results in lower PSA. So, if on ADT and your PSA is lower, but your T is not, then something else is going on. (Which ADT are you on?)
Replies to "Interesting. You say that you’re on ADT, your PSA is lower m, but your T is..."
I dug into this some and found this
Why T Levels Might Appear Normal:
In some cases, even with Lupron's effectiveness in lowering testosterone, the initial T levels might still be within the normal range. This is because some testosterone comes from sources other than the testicles, and Lupron primarily targets testicular testosterone production.
Lupron, a gonadotropin-releasing hormone (GnRH) agonist, suppresses testosterone production, leading to a decrease in PSA levels, even if T levels remain within the normal range. This occurs because PSA, a marker for prostate cancer, is influenced by testosterone. While T levels might remain in the normal range, Lupron effectively reduces the stimulation of prostate cells that produce PSA, resulting in a lower PSA count.
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Exactly! I’m not sure what’s happening. I am on Lupron and experiencing some obvious, not-so-great side effects, yet my T-levels are low normal. I have no pre-treatment T-levels for comparison. A lower PSA post-Lupron injection should correlate with a very low T-level. The last PSA test was rising slightly, so we'll see where this all goes. I’m considering stopping the Lupron and monitoring. The only treatment I am on that would lower the PSA is Lupron.