I am doing one year of Prolia then transitioning to something else. I haven't had any side effects but I don't want to push my luck. I have a consult with another endocrinologist at Duke who may be more creative. Unfortunately I've been on osteoporosis meds for awhile now... Alendronate,forteo, evenity, Prolia. I'd like to go back on evenity or try tymlos but not sure either is an option. I'll report back when I know more.