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I had a radical prostatectomy five years ago at the age of 61, with a Gleason of 7, 4+3, extraprostatic extension right bladder neck, and perineural invasion. Like you, there was no treatment after the RP; I monitored my PSA. For three years, my PSA remained < .1. Around three years in, it increased to 0.1. Dealing with other serious health issues, I failed to retest for almost a year. When I finally got tested about a year after the first reading of 0.1, my PSA had risen to .38. The doctor I had been seeing left the area, so since I live in a rural area, I had to find another doctor over 100 miles away. Another 45 days passed before I could see this new doctor, and my PSA was now at .48. I had a PSMA PET scan, which revealed lymph node metastasis. My PSA level continued to increase; 45 days later, it was at 0.78. I am now on ADT. My PSA has lowered, but my T-levels are now over 300. Perhaps signs of castrate resistance. All that said, if you're at PSA .2, I would consult with the experts. Best wishes!
Replies to "I had a radical prostatectomy five years ago at the age of 61, with a Gleason..."
It takes 2 to 3 months for most people to get their PSA down to undetectable. Your testosterone doesn’t go up if you are castrate resistant, more likely it just hasn’t gone down all the way, yet. If castrate resistant your PSA goes up even though you’re on ADT. Give it some time.
If your PSA does continue to rise while on ADT then you need an ARSI like Zytiga or a Lutamide, That can get your PSA down when ADT alone won’t do it.
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Interesting. You say that you’re on ADT, your PSA is lower m, but your T is not.
How ADT works —> ADT lowers T which results in lower PSA. So, if on ADT and your PSA is lower, but your T is not, then something else is going on. (Which ADT are you on?)