A biologic like Kevzara introduces another variable into the tapering process.

When I tried another biologic called Actemra, I tapered from 10 mg by 1 mg per month for the first 3 months. From 7 mg, I tapered by 1 mg per week down to 3 mg.

At 3 mg of prednisone, it was determined that my cortisol level was too low so I couldn't taper any lower than 3 mg for 6 months. After my cortisol level improved, my endocrinologist said 3 mg was such a low dose of prednisone there was no need for me to taper. I was told to simple stop taking Prednisone. As long as PMR was controlled AND my cortisol level stayed within an adequate range there was no need to taper from 3 mg of Prednisone to zero. I tapered anyway ... I decreased by 1 mg every couple of days to zero in less than a week.

Actemra did a fantastic job of controlling PMR so I don't need Prednisone anymore. My cortisol level improved the longer I was off Prednisone. My symptoms of adrenal insufficiency gradually disappeared.