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Capecitabine (Xeloda) side effects: how do you manage them?

Breast Cancer | Last Active: 4 days ago | Replies (33)
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@penelope74

TNBC dx 4/2024 on xeloda since January 2025, 2000mg 2xday, 2 wks on 1 week off. The plan is to continue through June 2025. My labs have been good but feeling more fatigue and difficulty concentrating for any length of time. I definitely know fatigue from IV and severe anemia etc.
Is this expected?
I want to get through this.
I am planning travel in October and tough to get anything done. Such as cooking, driving,,little things around the house. My spouse has picked up most of it.
Interested in hearing your experiences. Thank you

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Replies to "TNBC dx 4/2024 on xeloda since January 2025, 2000mg 2xday, 2 wks on 1 week off...."
sally484 | @sally484 | May 21 9:21am

Xeloda was the first drug I took. It affected my hands and feet. Made them very sore and tender and my skin peeled. Sometimes it was hard to even open a door. Asked to be taken off then went on Anastrozole.

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Colleen Young, Connect Director | @colleenyoung | 4 days ago

@penelope74, I moved your question about Xeloda side effects and fatigue to this existing discussion in the Breast Cancer group.
- Capecitabine (Xeloda) side effects: how do you manage them? https://connect.mayoclinic.org/discussion/xeloda-oral-chemo/

I did this so you can read previous posts and connect with others.

You might also be interested in this related discussion:
- Coping with fatigue: What are your coping tips?https://connect.mayoclinic.org/discussion/coping-with-fatigue/

How are you doing? Have you found coping mechanisms to help you manage your daily activities with the fatigue?

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