I have also been on osteo meds for years now - Prolia specifically. I encountered 2 compression fractures in my spine (I forget which vertebrae) after a fall and a car wreck 7 days later in January of 2024. I had these show on an xray but also an MRI to check the severity. My ortho surgeon did a kyphoplasty on both. The pain prior to surgery was unbearable., nothing like anything I have ever experienced. Then in April I somehow had another. I do not have any idea how this one happened. It was not as painful, but just felt like something wasn't right and went back to the doctor. Was actually shocked when he said I had another compression fracture! I had that one reparied via kyphplasty in June. I hurt all the time now and never sleep well. I worry there is another fracture I don't know about and quite frankly don't want to go find out about. Tough place to be. I did PT after the 2nd surgery and that helped tremendously. I have to stretch my back every morning now before I am able to move well and not hurt as much. It is certainly a very different life for me who was once not so long ago super active - running, walking, hiking, etc. I am afraid to do much now. One misstep seems to be a possible fracture. Recently had my scheduled bone scan and it was worse - after years on Prolia. I was so hopeful it would be better. My doctor wants me to change to Evenity and claims that is my only choice. I am researching Evenity becasue I had already had a conversation with the NP at the cancer clinic that administers the Prolia and the serious side effects of heart issues scare me. I don't have any heart issues, but do have serious heart disease in my family history. Does anyone use Evenity and have for some time with some stories to share?