@melissa123 - I did this weight loss medication change you mentioned because although I lost about 54 pounds on semaglutide (Wegovy - Ozempic for use in those who are diabetic) I had really harsh GI symptoms from the shots and was having trouble continuing. So, my doctor had me go off of semaglutide for a month to determine if my symptoms were indeed linked to the semaglutide or something other. They were, we learned.

I gained weight at an alarming rate while off the semaglutide, which my doctor confirmed was normal when I shared the figures with her.

She then started me on tirzepatide
(Zepbound, and Mounjaro for those with diabetes). I had to start at the very first dose and titrate up. I'm having very few side effects, but I'm also not feeling this med is holding me back from eating like the semaglutide by itself did.

My weight loss has been frustratingly low on my new med, like a pound. My doctor tells me to have patience.

Hoping this all works out favorably in the end.

Wow, how long were you off Wegovy for before you started back up on your new med? I would be switching right away. Also did you gain weight because you ate more? I hear people gain weight quickly if they go off the meds.

I switched from OZ 2.0 to Monjaro a few months back. Started at 5 mg for 2 months, then 10 mg for same and am now moving to 12.5 mg. Good news was @ 10 of Monjaro, my A1C went from 6.8 to 6.2 without me making any changes. No weight loss over same period. I had RNY bypass 38 years ago. No problem with switching meds. My issue was on day six, Monjaro half life was over and I felt hungrier. It took another day after new injection for it to work again. I wish Monjaro had a screw top as the large gray plug is hard to refrigerate and carry enough when traveling for a few weeks. Best of luck to you.

Good to know other feel the difference on day 6 & 7. All my best.

Ozempic doesn't take any food noise for me. That's why I wanted to switch.

Has anyone had chronic diarrhea since having roux-n-y (gastric bypass) surgery?

I was on Ozempic for a year and lost 110 pounds. I felt like after a year, I started to plateau and wasn't losing weight. The food noise started again. I talked to my doctor and she switched me to Mounjaro. From the time I quit Ozempic and am currently on 10 mg and am not feeling any difference in the noise. I've gained 45 pounds back in 2 months from the switch. My doctor is not very supportive and tells me to be patient also. I don't know how much longer I can hold on for the Mounjaro to start working for me. I am very frustrated and feel my doctor is dismissing my frustration. Any advice would be so appreciated. Thank you!!

I have been on mounjara for 7 months.My AIC is now 5.1 and 60 lbs lighter.

I have been on Monjuaro for 2 years after a short bout with Ozempic. I lost over 150 lbs. I just had a panniculectomy (tummy tuck) at Mayo. My excess skin weighed 4 lbs. Do not give up. The side effects are hard as are the food and or/drink choices you have to make. Stick with it and listen to your body about what goes in there. It is so worth it! I lost a whole person and feel amazing! You got this!! These medications are amazing. This is just the begging, it is working for heart disease, sleep apnea, fatty liver etc.