Understandable, and that's a very personal choice. We all have to balance quality and quantity of life.

I've lost track of your situation, but if your cancer is already metastatic, taking ADT together with one of the -lutamides now is more effective than waiting to add a -lutamide later (per TITAN, etc).

If your cancer becomes castrate-resistant, you still have good treatment options these days, but they can be tougher than just taking ADT and a -lutamide, so the longer you can delay castrate resistance, the better.

Best of luck, whatever you choose.