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← Return to Blood Clots from Chemo?
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For background, I had Whipple February 9th 2024, then 12 rounds of Folfirinox during which my CA19-9 never rose above 11, but then CT-scan 2 weeks later showed liver lesions and subcutaneous belly tumor. I had SBRT the first week of March. Restarted Gemcitabene/Abraxane in late April. I had a CT scan yesterday and am waiting for results, however I started having pain under my bottom right ribcage a week and a half ago, and so of course I am terrified this is new and the treatments are not working. If that's the case, is lipsomal irinotecan my next shot, or do I try to get into an RM6236 trial somewhere? I know you are not doctors but appreciate your thoughts. My CA19-9 is 132 right now, has not reliably come down but more bounces around. I am unfortunately KRAS G12V, and adenosquamous (the most aggressive type).
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I’m in the exact condition you are in - had to face those choices of Naliri or 6236. My CA19-9 (289) and CEA are rising and had 4 types of scans and MRI showed nothing and CT and PET ID’d maybe very small lesion in liver and high uptake 4.9 on gallbladder. I’ve only been on gemzar since January of this year and my numbers only started to go above normal limits at very end of April; so we are on a “witch” hunt now. I didn’t take the 6236 phase 3 trial because it’s randomized and only 50% get the target drug (it has a name now but I forget offhand its name); the arm I believe is the liposomal chemo. I rather look for surgical options if in liver or gallbladder. If in peritoneal area then I might try Claudin 18.2 if I can get it. Trouble I have with Naliri is that it can cause someone with lung disease to get worse and I have history of asthma and interstitial lung disease. It’s all a personal and I’ll be praying you find the right solution for you.