Hi kaki49. Both my rheumatologist and oncologist recommended Prolia. My oncologist has a handout sheet regarding taking Verzenio and Prolia at the same time. Ive not heard of Zometa. I now feel that the lesser of the two evils is to take Prolia rather than breaking a hip and the doctors NOT being able to repair it. Yes, we are in a mess. I keep praying that God will take care of me. AND, my dentist said she treats several patients who are taking Prolia with no issues. Hope this helps you and eases your mind, even if just a little. Blessings.