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Abiraterone alone for HT ADT therapy for PC

Prostate Cancer | Last Active: 23 minutes ago | Replies (19)
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@laccoameno5

So with an ARSI drug such as Abiraterone you still have testosterone in your system but a receptor signaling inhibitator is now present. So PC receptor cells can't recieve testosterone? Correct?
Ischia

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Replies to "So with an ARSI drug such as Abiraterone you still have testosterone in your system but..."
jeff Marchi | @jeffmarc | 1 day ago

Well, that is true with lutamide drugs.

Abiraterone acetate is a CYP17A1 enzyme inhibitor that blocks testosterone production at its source, complementing receptor signaling inhibitors by reducing available androgens. It reduces testosterone to undetectable levels.

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