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← Return to Taking Orgovyx long term
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Thanks for your suggestion. Is this to replace Orgovyx?
I started with Lupron monthly shots (for 7 months) and changed to Orgovyx (now for 5 months). The damage is done with these negative ADT side effects. On ADT now for 12 months and working on combating the worst effects of fatigue, hot flashes, muscle loss, and severe bone density loss. Urologic Oncologist recommends I continue with ADT for 6 more months to see if PSA stays low (at least at 0.01). At times I just hate all of this and other times I'm good.
Replies to "Thanks for your suggestion. Is this to replace Orgovyx? I started with Lupron monthly shots (for..."
My intent is to request switching from Orgovyx to Nubeqa at 12 months. There are some recent studies using Nubeqa alone, but it's apparently not considered Standard of Care yet. Typically doctors add Nubeqa to Orgovyx (ARPI + ADT) if PSA rises while on ADT, indicating the cancer has become castrate resistant. Nubeqa (ARPI) seems to have fewer side effects, and I would like to take it in advance of any PSA rise. Testosterone will begin returning but PSA should stay low. I've met someone online with recurrent (lymph node) cancer, and he is taking Nubeqa alone with undetectable PSA and no side effects. He's being treated by Dr. Kwon at Mayo Clinic.
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It’s too early for you to stop taking ADT. If you have many years with undetectable PSA, then dropping ADT early can make sense. I stopped ADT after eight years because it’s unlikely for my Testosterone to come back.
If ADT keeps your PSA undetectable, then you really don’t wanna change anything.