1. < Osteoporosis & Bone Health

Does Evenity get easier?

Posted by aspirecreative @aspirecreative, May 14 5:53pm

I had 1 shot of Evenity , followed by 7 weeks of joint and bone pain. I do have RA and it was the worst flare ever. I took a 2 month pause and am scheduled to start again. I am wondering if any one had a bad first reaction--bone and joint pain, but then found the subsequent ones were better. I am not sure if I am up for trying this again.

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dbamos1945 | @dbamos1945 | May 14 7:44pm

Following your situation with interest due to my Evenity beginning soon. Your feelings will influence my actions. Thanks & best outcomes…

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1 reply
hlp123 | @hlp123 | May 14 8:20pm

These decisions are so very difficult. I have been told by my endocrinologist that I have to take reclast or my bones will continue to fracture. Right now I am dealing with multiple fractures of my ribs and sacrum. I have also been advised that I cannot start reclast until all my bones have healed. I had X-rays and the results were no fractures, I then insisted on an MRI because I was in so much pain and it revealed five fractured ribs and "multiple" fractures of my sacrum. I don't know what to do. It seems everyone reacts differently to these medications, but my reactions to Prolia were severe !!!!!!! I would love to soak and I am considering buying a "walk in tub" Does anyone have any advise about which one to purchase. My shoulders are very painful and I would like to get a tub in which the water covers my shoulders.
I would really appreciate any advise. Feel as though I am in limbo, Don't know what to do. Thank you !!!!

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wilkenl | @wilkenl | May 16 6:03pm
In reply to @dbamos1945 "Following your situation with interest due to my Evenity beginning soon. Your feelings will influence my..." + (show)
@dbamos1945

Following your situation with interest due to my Evenity beginning soon. Your feelings will influence my actions. Thanks & best outcomes…

Jump to this post

I procrastinated starting Evenity for over a year, as I was very nervous both about the side effects and the effect on my long-term health. I finally started it in May 2024 and completed my 12th treatment in April 2025. The only side effect that I experienced was pain at the injection site for the first two or three treatments. About four hours after getting the shots (in my belly), it felt as if I had had surgery and the wound was in the process of healing. The sensation only lasted about eight hours. When I woke up in the morning, it was pretty much all gone. Other than that, I didn't notice anything other than little twinges here and there, not pain, just my body telling me where the medication was working, which, apparently it was! My spine had been at -3.4 when I started, and when I finished, it was at -2.6. I couldn't have been happier when I got those results.

There are many people who do suffer painful side effects with these medications, like @aspirecreative above. I think we don't hear as much from the folks who don't have side effects. That's why I mention my experience, to help alleviate your fears.

On a next-steps note, I just took my first Reclast treatment. Now that one I was really afraid of after reading the blogs! I went all out trying to prepare my body for it. I drank two quarts of water throughout the morning before my appointment, and then I asked the nurse to give me a saline drip alongside the medication. I also ate a non-inflammatory/anti-inflammatory diet for a couple of days beforehand, and I made sure that I took my magnesium (magnesium helps to relieve muscle pain). Lastly, I took my doctor's advice and took a 500 mg Tylenol about an hour before the infusion, and another one about four hours after. When I got home, I continued drinking lots of water and even an electrolyte drink. It's now been 48 hours since I finished my infusion. I have felt completely wrung out and tired, and I have no appetite, but that was about it for the first 24 hours. Last night, I developed pain in my eyes when I moved them right and left, so I went to see my optometrist this morning. He said that it was probably muscle pain - he didn't see anything that indicated anything more serious. All in all, it's been not too terrible so far.

I wish you all the best with your Evenity experience, @dbamos. I hope it goes easy for you.

Kind regards.

REPLY
1 reply
dbamos1945 | @dbamos1945 | May 16 10:43pm

@wilkenl: I really appreciate your detailed response to my reluctance to begin Evenity. You respond to new medications with proactive activity to eleviate side effects just like I do! I will follow your lead! Thanks!
I will also keep a list of the procedure you have used dealing with Reclast infusions for that may be in my future as well. Thank you again for preparing me with info on this osteoporosis road. 🙂 dbamos1945

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Mentor
Teresa, Volunteer Mentor | @hopeful33250 | May 17 9:48am
In reply to @wilkenl "I procrastinated starting Evenity for over a year, as I was very nervous both about the..." + (show)
@wilkenl

I procrastinated starting Evenity for over a year, as I was very nervous both about the side effects and the effect on my long-term health. I finally started it in May 2024 and completed my 12th treatment in April 2025. The only side effect that I experienced was pain at the injection site for the first two or three treatments. About four hours after getting the shots (in my belly), it felt as if I had had surgery and the wound was in the process of healing. The sensation only lasted about eight hours. When I woke up in the morning, it was pretty much all gone. Other than that, I didn't notice anything other than little twinges here and there, not pain, just my body telling me where the medication was working, which, apparently it was! My spine had been at -3.4 when I started, and when I finished, it was at -2.6. I couldn't have been happier when I got those results.

There are many people who do suffer painful side effects with these medications, like @aspirecreative above. I think we don't hear as much from the folks who don't have side effects. That's why I mention my experience, to help alleviate your fears.

On a next-steps note, I just took my first Reclast treatment. Now that one I was really afraid of after reading the blogs! I went all out trying to prepare my body for it. I drank two quarts of water throughout the morning before my appointment, and then I asked the nurse to give me a saline drip alongside the medication. I also ate a non-inflammatory/anti-inflammatory diet for a couple of days beforehand, and I made sure that I took my magnesium (magnesium helps to relieve muscle pain). Lastly, I took my doctor's advice and took a 500 mg Tylenol about an hour before the infusion, and another one about four hours after. When I got home, I continued drinking lots of water and even an electrolyte drink. It's now been 48 hours since I finished my infusion. I have felt completely wrung out and tired, and I have no appetite, but that was about it for the first 24 hours. Last night, I developed pain in my eyes when I moved them right and left, so I went to see my optometrist this morning. He said that it was probably muscle pain - he didn't see anything that indicated anything more serious. All in all, it's been not too terrible so far.

I wish you all the best with your Evenity experience, @dbamos. I hope it goes easy for you.

Kind regards.

Jump to this post

Hello @wilkenl,

I also appreciate your post about your experiences with medications for osteoporosis. As @dbamos1945 posted, I also need to make a decision about which drug to take for bone loss. I can tell that you followed a good protocol before starting treatment. I always admire a proactive approach, and yours was great!

You've provided some great encouragement!

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