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Happy and worried

Prostate Cancer | Last Active: May 22 8:14am | Replies (16)

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Profile picture for northoftheborder @northoftheborder

Sounds like Lupron (a shot every three months) and one of the -lutamides (I take 4 Apalutamide pills every day). If my guess is correct, then the goal is to put the cancer to sleep for a while by blocking androgens like testosterone (its main trigger) at both ends:

Lupron is an ADT, which blocks your body from producing testosterone.

The -lutamides are ARSIs, which block cancer cells from receiving testosterone and other androgens (even, to a certain extent, once tumours become castrate-resistant and evolve to produce their own androgens).

It sounds like a good first strategy to my layperson's ears. If they reduce your PSA to undetectable in a few months (especially on the uPSA test), then you'll know that the cancer has gone dormant.

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Replies to "Sounds like Lupron (a shot every three months) and one of the -lutamides (I take 4..."

I'm on exactly the same doublet therapy. Had a blood test test today(after three months on the protocol), and PSA is .01. Given that I'm 83, I'm hoping this might see me through for a few years. But who knows?