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Help needed comparing CTX & P1NP results
Osteoporosis & Bone Health | Last Active: 7 hours ago | Replies (12)Comment receiving replies
Thank you gently! Sure wish docs would share info; got these tests and there has been no communication of what results may mean. Will check videos; I've looked at some of the (I believe) Dr. Doug ones; informative. L-spine gained 3%, L-hip 2% and no change in L femoral neck in the year of Fosamax (no right info, hip replaced 10 years ago). Have heard (doc google) that too low CTX can sometimes predict a higher risk of ONJ so maybe it's time for a new drug? Doc wants Reclast but I am still in the process of getting multiple second opinions (ortho, gyne, my IBS doc for handling stomach issues on bisphosphonates, and a rheumatologist). I have been wondering about the bone building drugs...
Replies to "Thank you gently! Sure wish docs would share info; got these tests and there has been..."
jozer, the bone markers aren't prescribed by many physicians. Some consider the assays unreliable, and consequently without signification.
Fosamax represses bone turnover which increases the risk of osteonecrosis of the jaw and atypical femur fracture. Given your previous hip fracture and the lack of gain in the left hip, you might consider your density numbers in that left femur while considering your options.
Stomach issues on the injectable bisphosphonates are less problematic because they avoid the alimentary canal. If your IBS is not autoimmune it might not have to be a consideration.
I'm partial to the bone building drug Forteo.
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I am on TYMLOS for one year and I had RECLAST to start two years ago. I have IBS. So I am very careful when it comes to food and medicines. Unfortunately when I did the RECLAST, no one prepared me and I was only one month out from a double cervical spine surgery so it was probably not a good idea to do the RECLAST. I was one of the 10% who reacted to the drug unfavorably. I’ve had an experience like that before and so I chalked it up to needing the medicine. Sometimes when our system “fights“ something it’s with an immune system response and I had a severe reaction. It could’ve been controlled if I had known to drink the water and take Tylenol before I go in. As far as the TYMLOS I had the run-of-the-mill side effects the first two months. Again, I think it was my system reacting to needing the medicine.. From all the information I gathered “magically“ the side effects (being nauseous,, being fatigue, a little lightheaded, a little headache, achy, it all went away at two months. Also, someone here had recommended titrating up to the 80 units. So I started at 20 and once a week titrated up 10 units. we had conversation here about the belly and hip fat from Art injections. I’m not sure we could say it’s causal, but I think when you get good results, it confirms doing the medicine and overcoming the challenges. I grew up taking a ton of spills as my ankles were weak, and I was considered a klutz. So I just got used to picking myself up after I fell. Last year at age 68 I knew five women who fell and fractured or broke shoulders or hips in my circle. I’ll deal with the consequences of the medicine to get the improvement when they opened me up to do cervical surgery in 2023. My bone fell apart in their hands. I’ve taken DES every year for 25 years or more. Nothing prepared anyone for that. I’ll take the medicine.