This is helpful, as we will have a decision soon about which ARPI to follow 6 rounds of docetaxel + carboplatin unusual protocol. COE suggested ‘quad’ tx of ADT and that double chemo Plus Daralutamide all at once. Our local MO compromised with starting with ADT and the double chemo, followed by the ARPI when chemo is done. Both Abiraterone and Nubeqa have been suggested. I think our MOmis leaning to Abiraterone, so been reading and finding various views on which ARPI first, but no clinical studies on this quad tx and ways to sequence it. Any studies appreciated, although I have a spreadsheet full. On another forum someone said they are doing this quad protocol at MD Anderson, but I can’t find any trials or info. Anyway, thanks for this sequence thinking.