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What are the chances that this is just a PSA bounce?
Prostate Cancer | Last Active: May 16 6:36pm | Replies (14)Comment receiving replies
Hi Brian. I did have a PSMA pet scan before treatment that showed no spred. My gleason score was 3 + 4 but my Decipher was .95. That's when we did the PSMA scan and a decision was made against ADT. It's a bit early for a bounce but I'm hoping for the best.
Replies to "Hi Brian. I did have a PSMA pet scan before treatment that showed no spred. My..."
.95 Decipher and it was decided NOT to use ADT?
It seems to me that the Decipher score is much more informative in terms of PCa aggressiveness than a negative PSMA.
@jeffmarc recently informed the forum that PSMA doesn’t show anything unless it is 2.7mms. In diameter; other studies have shown it to be as high as 5mms.
Cannot say that your PSA increase is meaningful until you see a trend. Do you know if your IMRT included pelvic lymph nodes? They are often not treated when PSMA is negative, so please ask your RO if they were treated. If not, that may be where the PSA is coming from.
Phil
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It’s great that you used other test results to help in the decision.
> With your 3+4, what % was “3” and what % was “4”?
Hopefully, the recent PSA spike is just an aberration.
> How many sessions of radiation did you have?
> Did you use a rectal spacer (SpaceOAR, Barrigel, or BioProtect)?
On one occasion when my post-treatment PSA was a bit higher than expected, we repeated the PSA test in just a few weeks rather than waiting a few months. (Just something to consider bringing up with your RO.)