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What are the chances that this is just a PSA bounce?
Prostate Cancer | Last Active: Jan 16 11:01pm | Replies (19)Comment receiving replies
Keep checking PSA and look for a trend.
Did you have a PSMA PET scan prior to treatments? Did you have a biomarker (genomic) test?
PSA is expected to be below 0.50 following standard radiation treatments (and if ADT was used, after ADT was out of the system). You should ask your RO if the first PSA of 0.9 was normal and expected.
As for PSA bounce, that’s common following SBRT and brachytherapy (where there is an intense radiation dose); it’s less common for standard treatments of IMRT and proton. Also, PSA bounce is said to occur at 12 - 18 months out (and as far out as 2 - 3 years), and not usually so soon after treatments.
Watch this closely with another PSA test. (Since this is regarding radiation, I’d listen to my RO.)
Replies to "Keep checking PSA and look for a trend. Did you have a PSMA PET scan prior..."
@brianjarvis I was on Orgovyx starting March 26 and had my SBRT treatment in mid-April 2025. Three months post-SBRT my PSA ws 0.36; six months post-radiation and at two weeks off Orgovyx my PSA was 0.22; at 3-1/2 months off Orgovyx my PSA bounced back to 0.98. My scheduled consultation with the RO is at the end of January. Should I ask if that bounce is so soon based on your comment that "PSA bounce is said to occur at 12 - 18 months out (and as far out as 2 - 3 years) ..."? When I last saw my RO, she said that a rise in PSA will be normal if it correlates (can be explained by) a corresponding rise in my T level. My libido and erection is back to pre-ADT; I don't have a pre-treatment T baseline number, so can't say if T is back as well.
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Hi Brian. I did have a PSMA pet scan before treatment that showed no spred. My gleason score was 3 + 4 but my Decipher was .95. That's when we did the PSMA scan and a decision was made against ADT. It's a bit early for a bounce but I'm hoping for the best.